求翻译：本次试验给药3月和6月，给药大鼠肾脏的重量、脏器系数以及脏脑比与对照组比较，均有明显升高，尤其是中、高剂量组有持续性改变。是什么意思？

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This test in March and June to medicine, and medicine to rat kidney weight, organ factor, as well as dirty and the contrast group than brain, there has been an obvious rise, particularly in high-dose Group, there is continuous change.

This experiment for medicine in March and in June, for the medicine big mouse kidney weight, the internal organs coefficient as well as the dirty brain compares compared to and the control group, has the obvious ascension, the high monitoring team has the long-enduring change in particular.

In this experiment to the drug in March and June, administration of rat kidney weights and organ coefficient and filthy brain than compared with control groups are significantly increased, in particular, high dose group, sustainable change.

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