1.Variola virus belongs to the genus of orthopoxvirus, and there are some other infectious members, such as Vaccinia virus, cowpox virus, and monkeypox virus.
2.Modified vaccinia virus Ankara;
3.Some virus genome of vaccinia subgenus in poxvirus encoded IL-18BP gene, which can block IL-18 activity but no sequence similarity to membrane IL-18 receptors.
4.And the international AIDS pandemic vaccine design and technology very different routes, China's ongoing clinical trials is replicating vaccinia virus vector, belonging to the vaccine.
5.The relationship between virulence and the size of the plaques of recombinant vaccinia viruses was studied by plaque assay method on chicken embryo cell monolayer with AGAR overlay.
6.The results showed that the recombination frequency of these rMVAs was significantly high, though lower than that observed in other vaccinia virus strains.