求翻译：一些外界因素如温度、溶剂、pH、离子强度等均会影响蛋白质的折叠，使其部分或全部失去生物学活性，引起蛋白质分子的物理化学性质的异常变化，这一过程称为蛋白质的变性。是什么意思？

External factors such as temperature, solvent, ph, ionic strength, etc. will affect the protein folding, it partial or total loss of biological activity caused by physical and chemical properties of the protein molecules of abnormal changes in a process known as protein denaturation.

Some external factors such as temperature, solvent, such as strength, ion pH will all affect the protein folding, make some or all of its active ingredients, and biology lost protein molecule from the physico-chemical nature of the changes, a process known as proteins denatured.

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A number of external factors such as temperature, solvent, pH, ionic strength, will affect the protein's fold, its partial or total loss of biological activity, causing abnormal changes of physical and chemical properties of the protein molecule, this process is called denaturation of the protein.

Some outside factor like temperature, the solvent, pH, the ion intensity and so on can affect the protein the fold, causes its part or loses the biology activeness completely, causes the protein member physico-chemical properties exceptionally change, this process is called the protein the denaturat