求翻译：摘要：探讨系统性红斑狼疮(SLE)合并狼疮性肾炎(LN) 患者应用大剂量环磷酰胺冲击治疗的护理。由于病程迁延，病情反复，加上大剂量环磷酰胺冲击治疗狼疮肾炎需要多次反复进行以及严重的不良反应，给患者带来身心多方面的疲惫。因此，全面、细致的护理对保证治疗的顺利实施、减少并发症等方面起着重要作用。是什么意思？

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