求翻译：遗传变异在冠心病（CHD）的发病过程中起重要作用，GWAS 已发现许多与CHD 关联的常见变异，却不能建立低频和罕见变异与CHD的关系。利用外显子SNP芯片技术，在2000对CHD-对照中发现新的和显著性差异的SNP，尤其是低频和罕见变异，进而在队列人群的2000对CHD-对照中验证，对人群中重要发现进一步研究其机制，揭示CHD发病关键的致病位点或基因，为CHD个体化预防、早筛查和早诊断提供科学依据。是什么意思？

Genetic variation plays an important role in the incidence of coronary heart disease (chd) process the, gwas found chd associated common variants, but not the establishment of low frequency and rare variants chd relationship. Use of exon snp chip technology, in 2000 chd-control found new's and signi

Genetic variation in coronary artery disease (disease of CHD) play an important role in the process, GWAS CHD has been found associated with the common variant, but it is not a rare mutation frequency and the relationship with CHD . Using the external graphics subsystem SNP chip technology, in 2000

Genetic variation in patients with coronary heart disease (CHD) play an important role in the pathogenesis, GWAS has found many common variations associated with CHD, it did not build low frequency variation and relationship between CHD and rare. Using outside display child SNP chip technology, in 2