求翻译：支气管哮喘是由多种因素引起的疾病，目前公认的发病机理主要是气道炎症假说。最近研究发现胰岛素受体底物在支气管哮喘发病中也起很大作用，通过探索胰岛素受体底物（Insulin receptor substrate，IRS）如IRS-1，IRS-2和SHc（SHc是含有SH结构域的基因编码的蛋白产物），尤其是SHc，在支气管哮喘患者中的作用机理，将有望在哮喘治疗上提出新的治疗方向。是什么意思？

Bronchial asthma is a disease caused by a variety of factors, the currently accepted pathogenesis of airway inflammation hypothesis. Recent studies have found that insulin receptor substrate also played a significant role in the pathogenesis of bronchial asthma, by exploring the insulin receptor sub

Bronchial asthma is caused by a variety of factors, the disease is now recognized as the pathogenesis is primarily airway inflammation hypothesis. Recent studies found that insulin receptors on bronchial asthma, the disease also played a large role in insulin by exploring the bottom substrate (Insul

Bronchial tube asthma is disease which causes by many kinds of factors, at present recognizes the pathogenesis mainly is the gas channel inflammation hypothesis.Recently studied the discovery insulin acceptor substrate also to play in the bronchial tube asthma morbidity the very major role, (Insulin

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bronchial asthma is caused by a variety of factors, the disease is now recognized as the pathogenesis is primarily airway inflammation hypothesis. Recent studies found that insulin receptors on bronchial asthma, the di