求翻译：这个课题有三个方面的难题：按照已有的合成方法产率低；底物在热条件下不稳定，而更难的是不知道这个反应在那种条件下得到目标产物，同时原料在热条件下的不稳定性带来的问题是不能在加热的条件下促进反应的进行。是什么意思？

This issue has three aspects of the problem: According to the existing synthetic methods produce low; substrate in the thermal conditions of instability, while the more difficult does not know the reaction under conditions that the target product, while material in the hot conditions under the insta

There are three aspects of the subject in accordance with a dilemma: output of synthetic methods is low; thermal conditions in the property is not stable, and it is much more difficult to don't know what the response under conditions in which the target product, while raw materials in thermal condit

This topic has three aspect difficult problems: According to the synthetic method production rate which has has been low; The substrate is unstable under the hot condition, but more difficult not to know this response obtains the goal product under that kind of condition, simultaneously raw material

This subject three challenges: under existing synthesis method yields low substrates in unstable thermal conditions, more difficult is what this reaction in that condition are the target product while raw materials in thermal conditions of instability problems cannot bring under heating conditions t

This subject three challenges: under existing synthesis method yields low substrates in unstable thermal conditions, more difficult is what this reaction in that condition are the target product while raw materials in thermal conditions of instability problems cannot bring under heating conditions t