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  • 匿名
关注：1 2013-05-23 12:21

求翻译：Examination of cells from the only known human patient presenting with accelerated aging associated with ERCC1-XPF deficiency revealed no influence on recombination in either telomeric or genomic DNA (i.e., T- and G-SCE frequencies were not affected in this background). Either the residual level of ERCC1-XPF activity i是什么意思？

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Examination of cells from the only known human patient presenting with accelerated aging associated with ERCC1-XPF deficiency revealed no influence on recombination in either telomeric or genomic DNA (i.e., T- and G-SCE frequencies were not affected in this background). Either the residual level of ERCC1-XPF activity i
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  • 匿名
2013-05-23 12:21:38
从检查的唯一已知的人类患者与ERCC1-XPF缺乏相关的加速老化提呈细胞的发现无论是端粒和基因组DNA（即T-和g-SCE频率并没有受到影响在此背景下）的重组没​​有影响。无论是在单个ERCC1-XPF活性的残留水平足以绕过升高的SCE型，或ERCC1-XPF不是叔SCE抑制器，并且可能实际上需要为它们的形成。无论，与这种情况相关联的早衰不可能通过端粒超重组介导的。相反，过早衰老可能已造成复制衰老的nontelomere相关的机制，或由端粒储备的耗竭所带来的升高率细胞更新，以弥补经常性​​细胞死亡。
  • 匿名
2013-05-23 12:23:18
Examination of cells from the only known human patient presenting with accelerated aging associated with ERCC 1-XPF deficiency revealed no influence on recombination in either telomeric or genomic DNA (i. e., T - and G - SCE frequencies were not affected in this background). Either the residual leve
  • 匿名
2013-05-23 12:24:58
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  • 匿名
2013-05-23 12:26:38
Examination of cells from the only known human patient presenting with accelerated aging associated with ERCC1-XPF deficiency revealed no influence on recombination in either telomeric or genomic DNA (i.e., T- and G-SCE frequencies were not affected in this background). Either the residual level of
  • 匿名
2013-05-23 12:28:18
Examination of cells from the only known human patient presenting with accelerated aging associated with ERCC 1-XPF deficiency revealed no influence on recombination in either telomeric or genomic DNA (i. e., T - and G - SCE frequencies were not affected in this background. Either the residual level
 
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