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  • 匿名
关注:1 2013-05-23 12:21

求翻译:Recently, it has been reported that compounds bearing a sulfonamide moiety posses many types of biological activities, including anticancer activity. There are a variety of mechanisms for their anticancer activity, and the most prominent mechanism is the inhibition of carbonic anhydrase (CA) isozymes. The present work 是什么意思?

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Recently, it has been reported that compounds bearing a sulfonamide moiety posses many types of biological activities, including anticancer activity. There are a variety of mechanisms for their anticancer activity, and the most prominent mechanism is the inhibition of carbonic anhydrase (CA) isozymes. The present work
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  • 匿名
2013-05-23 12:21:38
最近,据报道,轴承磺基具有多种类型的生物活性,包括抗癌活性的化合物。有多种机制,其抗癌活性,而最突出的机制是抑制碳酸酐酶(CA)同工酶。目前的工作报告,一些新的噻唑[4,5-B] pyrane,噻唑[4,5-B]吡喃并[2,3-D]嘧啶衍生物轴承磺基合成。这些化合物的结构设计符合CA抑制抗癌药物药效的要求。新合成的化合物进行了评估其对人类乳腺癌细胞系(MCF7)在体外抗癌活性。筛选化合物最有趣的细胞毒活性比较作为参考药物阿霉素。化合物5,6,10和12(IC(50)值分别为39.4微米,41.6微米,35.72微米和34.64微米),表现出较高的杀伤活性高于参考药物阿霉素(IC(50)= 71
  • 匿名
2013-05-23 12:23:18
  • 匿名
2013-05-23 12:24:58
  • 匿名
2013-05-23 12:26:38
  • 匿名
2013-05-23 12:28:18
 
 
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